NOTE: Glioblastoma samples with a “GBM” prefix were short-term neurosphere cultures derived from primary glioblastoma xenograft lines serially passaged in mice. Samples with a “T” prefix were prospectively enriched CD133+ glioblastoma stem cells. Samples with a “VU” prefix were primary cultures directly isolated from patient surgical specimens (passage 3–7). IC₅₀ values were determined after 5-day JQ1 treatment. The maximal effects (E_max) represented the inhibition rates of JQ1 at 5 μmol/L. Data represent the mean of 3 independent experiments.

Abbreviations: vIII, EGFR variant III; HD, homozygous deletion; ND, not determined.