Table 2.

Multivariate analysis comparing the 27-gene model with molecular variables and UAMS, IFM, and UK gene-risk models in pPCL series

CovariatesHRalo95%CIbup95%CIbP
27-gene model33.282.77400.095.73E-03
del(13q)4.890.3764.922.29E-01
27-gene model20.542.42174.385.61E-03
del(17p)0.930.194.419.24E-01
27-gene model36.372.76478.676.27E-03
gain(1q)0.370.052.843.39E-01
27-gene model19.072.23163.117.10E-03
del(1p)0.970.24.669.72E-01
27-gene model353.19383.613.61E-03
t(11;14)3.20.47222.36E-01
27-gene model20.262.35174.386.15E-03
MAF-translocations1.280.266.417.65E-01
27-gene model16.281.79148.151.33E-02
del(8p)0.830.144.818.33E-01
27-gene model16.301.68158.461.61E-02
UAMS 70-gene model1.870.3410.214.70E-01
27-gene model19.922.30172.946.66E-03
UAMS 17-gene model1.240.226.928.08E-01
27-gene model20.542.43173.925.56E-03
IFM 15-gene model0.790.154.207.79E-01
27-gene model20.632.40177.535.84E-03
UK 6-gene model1.380.296.516.83E-01

NOTE: The model was available for all covariates with the exception of t(4;14), due to the low number of occurrence, and of ASCT, whose occurrence was inversely correlated with being part of the high-risk group that prevented the calculation of hazard ratio model in relationship with the configuration of survival data versus value of covariates.

aHR, hazard ratio; blo95%CI, up95%CI, lower and upper limits, respectively, of the 95% confidence interval of the hazard ratio.