Table 1.

Patient characteristics according to low and high MSLN scores

Patient characteristicAll (N = 1,209)MSLN score low (N = 1,097)MSLN score high (N = 112)P
Age, years, mean ± SD67.9 ± 6.967.8 ± 9.968.6 ± 9.20.50
Sex<0.001
 Male469 (39)405 (37)64 (57)
 Female740 (61)692 (63)48 (43)
Smoking history<0.001
 Current168 (14)147 (14)21 (19)
 Former828 (69)740 (68)88 (78)
 Never 208 (17)205 (19)3 (3)
Pack-years, median30 (10–54)30 (6–53)40 (25–60)<0.001
Stage0.466
 I987 (82)900 (82)87 (78)
 II129 (11)115 (11)14 (13)
 III93 (7)82 (7)10 (9)
Histologic subtype<0.001
 Solid/micropapillary295 (26)276 (26)19 (18)
 Acinar/papillary741 (64)665 (63)76 (74)
 Lepidic120 (10)112 (11)8 (8)
Lymphatic invasion0.92
 Yes487 (40)441 (40)46 (41)
 No722 (60)656 (60)66 (59)
Vascular invasion0.16
 Yes366 (30)339 (31)27 (24)
 No843 (70)758 (69)85 (76)
Visceral pleural invasion0.39
 PL0779 (65)699 (64)80 (71)
 PL1336 (28)309 (28)27 (24)
 PL277 (6)73 (7)4 (4)
 PL317 (1)16 (1)1 (1)
Mutation status<0.001
 No EGFR or KRAS mutation471 (60)421 (60)50 (63)
KRAS mutation200 (25)171 (24)29 (36)
EGFR mutation116 (15)115 (16)1 (1)

NOTE: Smoking history, histologic subtype, and mutation status were available from 1,204, 1,156, and 787 patients, respectively. Data are presented as number (%), unless otherwise noted.