Table 1.

Clinical data from patients with colon cancer and diverticulosis in the search for mucosa- or tumor-associated and internalized E. coli

Patients with colon cancerPatients with diverticulosis
Patients, n5033
Age70.5 ± 11.458.0 ± 11.9b
Sex, male/female28/2213/20
Presence of colon-associated E. coli, n (%)
 MucosaYes45 (90)29 (88)
No5 (10)4 (12)
 TumoraYes41 (93)
No3 (7)
Presence of colon-internalized E. coli, n (%)
 MucosaYes27 (54)16 (48)
No23 (46)17 (52)
 TumoraYes38 (86)c
No6 (14)
Presence of B2 phylotype E. coli strains
Yes31 (65)d13 (39)
No17 (35)20 (61)
Presence of cyclomodulin-positive E. coli strains
Yes26 (60)e6 (26)
No17 (40)17 (74)
  • aSix are undetermined.

  • bP = 0.03.

  • cP < 0.0002; tumor versus mucosa of patients with colon cancer or diverticulosis.

  • dP = 0.04; in both the mucosa and tumors of patients with colon cancer versus diverticulosis.

  • eP = 0.01; in both the mucosa and tumors of patients with colon cancer versus diverticulosis.