Table 2.

Characteristics of E. coli strains isolated from the colon cancer samples according to TNM status

TNM status
IIIIII/IV
Number of patientsa, n141519
Presence of E. coli, n (% of patients)No3 (21%)*1 (7%)1 (5%)
Yes11 (79%)14 (93%)18 (95%)
Phylogroup, n (% of patients)A6 (43%)2 (13%)6 (32%)
B15 (36%)4 (27%)4 (21%)
B26 (43%)12 (80%)c13 (68%)c
D5 (36%)4 (27%)5 (26%)
Cyclomodulin-positive strainb, n (% of patients)+5 (45%)9 (64%)c12 (67%)c
6 (55%)5 (36%)6 (33%)
pks-positive strain, n (% of patients)+4 (36%)8 (57%)d9 (50%)d
7 (64%)6 (43%)9 (50%)
  • aUndetermined for 2 patients (one patient with stage I tumor and other with stage III tumor).

  • bThe presence of genes coding for the cyclomodulins CNF, CDT, CIF, and colibactin (pks island) was analyzed.

  • cP < 0.05.

  • dP < 0.05.

  • *P < 0.05.