Table 1.

Chromosome imbalance regions in LINE-1–hypomethylated tumors

CytobandAberrationStart positionStop positionSizeCandidate gene−log10 (P)
1q21Gain1432243221501458456921524LOC1001300001.30102999
1q21Gain150145845150437139291295ANP32E, CA141.30102999
1q21Gain15043713915394985935127211.30102999
1q21Gain153949859154295703345845JTB, RAB131.30102999
1q21Gain15429570315530911210134101.30102999
1q22Gain155309112155904332595221ASH1L, MIR5551.30102999
1q21Gain155904332156796795892464S100A41.30102999
1q21–22Gain1568159421615691024753161NTRK1,INSRR1.30102999
1q42Gain19680081722532862428527808CNIH31.30102999
1q42Gain2253349592273168321981874DNAH14,LBR1.30102999
1q44Gain24873889824878954050643OR2T101.30102999
1q21Gain248789540249211884422345LOC1001300001.30102999
2q21Gain50765550520534681287919FSHR, NRXN11.30102999
2q35Loss219296581219500621204041VIL1,USP371.30102999
3q21Loss5073380350889948156146DOCK3,p21.21.30102999
3q21Loss514749595148648511527VPRBP1.30102999
3p14Loss711184657112943010966FOXP1,p131.30102999
3q13Gain11795018116220997444259794IGSF111.30102999
3q29Gain19313243619315687924444ATP13A4,q291.30102999
3q29Gain1931568791949643801807502C3orf21,q291.30102999
4q25Loss113504214113802089297876C4orf21,LARP71.30102999
4q28Loss128854114129114533260420MFSD81.30102999
5p15Gain22361325635132739SDHA, p15.331.30102999
5p15Gain82200588752065516ZDHHC111.30102999
5p15Gain9197190147493665552177SEMA5A1.30102999
5q31Loss1258916761258967495074ALDH7A11.30102999
6p21Loss325426943256506422371HLA-DRB11.30102999
6q22Gain125315619125934949619331RNF2171.30102999
6q23Gain134625874134958897333024SGK1,CpG:211.30102999
7p22Gain18867242203806317083MAD1L1,CpG1.30102999
7p21Gain72833092689387819610570C1GALT11.30102999
7q31Gain269302685571285928782592LANCL21.30102999
7q11Gain69085548705374281451881AUTS2,CpG1.30102999
7q21Gain78545354863672447821891MAGI21.30102999
7q21–22Gain92247365966657174418353CDK61.30102999
7q31Gain1078251481107141122888965NRCAM1.30102999
8q11Gain49434350545859795151630EFCAB1,SNAI21.30102999
8q21Gain75130234795745354444302JPH1,GDAP11.30102999
8q22Gain10506801412011597415047961RIMS2,TM7SF41.30102999
8q24Gain1312753421409559829680641ASAP11.30102999
9q21Gain822611099464972812388620TMC1,TLE4,TLE11.30102999
9q22Gain1041056041099378865832283BAAT, MRPL501.30102999
9q33Gain1178483151219379524089638TNC, DEC11.30102999
10q11Gain526857296341358310727855PRKG1,MIR605,ZNF488,RBP31.30102999
10q11Gain77139109832862746147166LOC441666,ZNF5031.30102999
10q26Gain1243482511243517783528DMBT1,q26.131.30102999
11p11Gain4917028049714750544471FOLH11.30102999
11q22Gain107091691107502415410725CWF19L21.30102999
12p13Gain2690550278628895739CACNA1C1.30102999
12p12Gain21613937216229749038PYROXD11.30102999
12p11Gain3366399834591668927671ALG10,CpG:251.30102999
17q11Gain31344645331569781812334ACCN1,CCL21.30102999
17q21Gain3909247239890632798161KRT23,KRT391.30102999
20p13Gain63430322549363419150603DEFB125,BMP2,HAO11.30102999
20q12–13Gain4067450841626812952305PLCG1,ZHX3,PTPRT, q121.30102999
20q13Gain60895001620703671175367BMP7,SPO11,LAMA5,RPS211.30102999
XGain6206353715478859792725061SPIN41.30102999
YLoss179720562606697280949171.30102999
YLoss2854842628784095235670CpG:32,q11.231.30102999