Table 2.

Cox models for disease-specific death

Model 1Model 2
Prognostic factorNa% DeadHR (95% CI)PHR (95% CI)P
M-category
 M1a or M1b2665.4%10.00610.019
 M1c6782.1%2.2 (1.3–4.0)1.9 (1.1–3.4)
NY-ESO-1–specific T cellsNot considered
 Present4866.7%10.041
 Absent4588.9%1.7 (1.02–2.9)
Melan-A–specific T cellsNot considered
 Present3873.7%10.067
 Absent5580.0%1.6 (0.97–2.8)
MDSCs
 ≤11%4575.6%10.19910.029
 >11%4879.2%1.4 (0.84–1.3)1.7 (1.1–2.7)

NOTE: Significant findings in the final models are shown in bold. Model 1 was adjusted for the confounding effects of Melan-A–specific T cells and CD14+CD11b+HLA-DR−/low MDSCs and no confounding or significant interactions were detected in model 2.

  • aOne patient had an unknown M-category and was excluded.