Table 1.

MOC line conservation with common HNSCC TCGA mutations

MOC1MOC22MOC23MOC2/2-10
1. CDKN2A
2. TP53V170E and splice siteT122P, K384*Splice siteE225*
3. JUB
4. CASP8R88S
5. PIK3CAOtherOtherOtherOther
6. NSD1N265I
7. NOTCH1splice siteOtherG1195R + splice site
8. FAT1E2054DD2756VK243*W3896R
9. MLL2S4691*Q1695LQ3647L
10. EPHA2K946*
16. HRASQ61LQ61LQ61LOther

NOTE: “Other” indicates that mutations in other genes involved in this pathway were identified. See Supplementary Table S5.