Table 2.

Efficacy results

Outcome studiedNumber of patients (n = 83; %)
Responses, number of patients (%)
 PR33
 SD42
 PD8
ORR, % (95% CI)33 (29.2–51.1)
6-month PFS, % (95% CI)51.3 (39.1–62.3)
PFS, months [median (95% CI)]6.1 (5.8–6.4)
OS, months [median (95% CI)]14.8 (12.4–19.2)

Abbreviations: ORR, Objective Response Rate; OS, overall survival; PD, progressive disease; PFS, progression-free survival; PR, partial response; SD, stable disease.