Table 5.

The diagnostic values of the panel of three sputum miRNA biomarkers in an internal testing set and an external testing set of specimens

An internal testing set of 122 patients with either malignant (n = 67) or benign SPNs (n = 69)An external testing set consisting of 155 subjects with either malignant (n = 76) or benign SPNs (n = 79)
Sensitivity82.09%80.52%
Specificity88.41%86.08%
PPV (95% CI)87.30% (76.89–93.42)84.93% (74.99–91.37)
NPV (95% CI)83.56% (73.43–90.34)81.93% (72.30–88.73)

Abbreviation: CI, confidence interval.