Demographics and baseline characteristics for once-daily and twice-daily regimens
| Once-daily regimen (N = 38) | Twice-daily regimen (N = 57) | |
|---|---|---|
| Mean (SD) age, years | 57.5 | 60.0 |
| Gender, n (%) | ||
| Male | 23 (61) | 37 (65) |
| Female | 15 (39) | 20 (35) |
| ECOG performance status, n (%) | ||
| 0 | 15 (39) | 17 (30) |
| 1 | 18 (47) | 28 (49) |
| 2 | 5 (13) | 12 (21) |
| Tumor type, n (%) | ||
| Colorectal | 12 (32) | 35 (61) |
| Pancreatic | 5 (13) | 2 (4) |
| Gastric | 4 (11) | 1 (2) |
| NSCLC | 0 | 4 (7) |
| Renal | 2 (5) | 1 (2) |
| Esophageal | 2 (5) | 1 (2) |
| Sarcoma | 1 (3) | 3 (5) |
| Melanoma | 1 (3) | 2 (4) |
| Breast | 1 (3) | 0 |
| Adrenal carcinoma | 1 (3) | 0 |
| Ovarian | 1 (3) | 0 |
| Others | 8 (21) | 8 (14) |
NOTE: Baseline characteristics of all patients who enrolled in the study including those in the expansion cohorts (n = 31; twice-daily regimen).
Abbreviation: NSCLC, non–small lung cell carcinoma.