Table 1.

Demographics and baseline characteristics for once-daily and twice-daily regimens

Once-daily regimen (N = 38)Twice-daily regimen (N = 57)
Mean (SD) age, years57.560.0
Gender, n (%)
 Male23 (61)37 (65)
 Female15 (39)20 (35)
ECOG performance status, n (%)
 015 (39)17 (30)
 118 (47)28 (49)
 25 (13)12 (21)
Tumor type, n (%)
 Colorectal12 (32)35 (61)
 Pancreatic5 (13)2 (4)
 Gastric4 (11)1 (2)
 NSCLC04 (7)
 Renal2 (5)1 (2)
 Esophageal2 (5)1 (2)
 Sarcoma1 (3)3 (5)
 Melanoma1 (3)2 (4)
 Breast1 (3)0
 Adrenal carcinoma1 (3)0
 Ovarian1 (3)0
 Others8 (21)8 (14)

NOTE: Baseline characteristics of all patients who enrolled in the study including those in the expansion cohorts (n = 31; twice-daily regimen).

Abbreviation: NSCLC, non–small lung cell carcinoma.