Table 1.

Clinical characteristics of the patients and tumor samples used in study

Both setsDiscovery setValidation set
Characteristicn (%)n (%)n (%)P
Number of tumors19884 (42)114 (38)
Age192841080.02
 <50 y81 (42)43 (51)38 (35)
 ≥50 y111 (58)41 (49)70 (65)
 Missing606
Race194801140.10
 Caucasian187 (96)75 (94)112 (98)
 Asian/Pacific Islander7 (4)5 (6)2 (2)
 Missing440
Menopausal status16771960.24
 Premenopausal62 (37)31 (44)31 (32)
 Menopausal11 (7)3 (4)8 (8)
 Postmenopausal94 (56)37 (52)57 (59)
 Missing311318
Body mass index166651010.65
 Underweight (<18.5)3 (2)2 (3)1 (1)
 Normal (18.5–24.9)46 (28)17 (26)29 (29)
 Overweight (25–29.9)61 (37)26 (40)35 (35)
 Obese (≥30)56 (33)20 (31)36 (35)
 Missing321913
Tumor size195831120.01
 <2 cm35 (18)10 (12)25 (22)
 2–5 cm139 (71)60 (72)79 (71)
 >5 cm12 (6)10 (12)2 (2)
 Any size with direct extension9 (5)3 (4)6 (5)
 Cannot be assessed312
Positive lymph nodes15066840.14
 074 (49)29 (44)45 (54)
 1349 (33)28 (42)21 (25)
 4917 (11)6 (9)11 (13)
 >1010 (7)3 (5)7 (8)
 Unknown481830
Metastases14664820.86
 No metastases144 (99)63 (98)81 (99)
 Metastases found2 (1)1 (2)1 (1)
 Unknown522032
Histology19884114
 Infiltrating ductal carcinoma188 (95)82 (98)106 (93)0.41
 Infiltrative lobular carcinoma1 (0.5)0 (0)1 (1)
 Adenocarcinoma/carcinoma, not otherwise specified7 (3.5)2 (2)5 (4)
 Medullary carcinoma2 (1)0 (0)2 (2)