Table 2.

Most frequent all-grade (>25% of total patients) and grade ≥3 (>10% of total patients) AEs, regardless of causality

Preferred termCLL (n = 10)Lymphoma (n = 15)Total (N = 25)
All-grade AEs, regardless of causality, n (%)
 Patients with any AE10 (100)15 (100)25 (100)
 Diarrhea8 (80.0)15 (100)23 (92.0)
 Pyrexia6 (60.0)7 (46.7)13 (52.0)
 Fatigue4 (40.0)7 (46.7)11 (44.0)
 Anemia3 (30.0)7 (46.7)10 (40.0)
 Cough3 (30.0)7 (46.7)10 (40.0)
 Nausea4 (40.0)6 (40.0)10 (40.0)
 Back pain3 (30.0)5 (33.3)8 (32.0)
 Dyspnea3 (30.0)5 (33.3)8 (32.0)
 Neutropenia5 (50.0)3 (20.0)8 (32.0)
 Rash2 (20.0)6 (40.0)8 (32.0)
 Upper respiratory tract infection6 (60.0)2 (13.3)8 (32.0)
 Hyperglycemia4 (40.0)3 (20.0)7 (28.0)
 Vomiting2 (20.0)5 (33.3)7 (28.0)
Grade ≥3 AEs, regardless of causality, n (%)
 Patients with any grade ≥3 AE10 (100)12 (80.0)22 (88.0)
 Neutropenia5 (50.0)3 (20.0)8 (32.0)
 Diarrhea3 (30.0)2 (13.3)5 (20.0)
 Anemia1 (10.0)3 (20.0)4 (16.0)
 Hypotension2 (20.0)1 (6.7)3 (12.0)