Table 1.

Cell surface expression of PD-L1 and PD-L1 mRNA abundance in lung cancer cell lines classified according to oncogene status and histology

Cell line	EGFR status	ALK status	Histology	PD-L1 mRNA^a	Surface PD-L1^b
HCC827	del(E746–A750)	Wild-type	Adeno	30.93	442.74
H1975	L858R+T790M	Wild-type	Adeno	21.65	355.92
PC9	del(E746–A750)	Wild-type	Adeno	13.41	278.39
11_18	L858R	Wild-type	Adeno	9.54	130.18
H1650	del(E746–A750)	Wild-type	Adeno	3.04	111.44
H2228	Wild-type	EML4–ALKv3	Adeno	11.98	275.88
H3122	Wild-type	EML4–ALKv1	Adeno	9.86	231.03
H322	Wild-type	Wild-type	Adeno	0.75	45.23
A549	Wild-type	Wild-type	Adeno	0.75	28.17
1-87	Wild-type	Wild-type	Adeno	0.57	71.88
LK87	Wild-type	Wild-type	Adeno	0.46	26.89
H23	Wild-type	Wild-type	Adeno	0.42	14.95
H2122	Wild-type	Wild-type	Adeno	1.85	43.93
H1437	Wild-type	Wild-type	Adeno	1.82	26.10
H1573	Wild-type	Wild-type	Adeno	0.76	35.11
H1944	Wild-type	Wild-type	Adeno	2.24	48.13
H157	Wild-type	Wild-type	Adenosquamous	12.61	138.37
H596	Wild-type	Wild-type	Adenosquamous	5.39	80.87
H460	Wild-type	Wild-type	Large cell	1.67	22.53
H1299	Wild-type	Wild-type	Large cell	0.95	54.44

Abbreviation: Adeno, adenocarcinoma.

↵^aPD-L1 mRNA abundance was determined by RT and real-time PCR analysis and was normalized by that of 18S rRNA.
↵^bSurface expression of PD-L1 was determined by flow cytometry and is presented as MFI values.