Table 1.

Patient characteristics

Characteristicn (%)
Total patients50
T-stage (tumor size obtained with breast ultrasound and/or mammogram)
AJCC clinical stagea
Tumor grading
 Grade I0
 Grade II7
 Grade III39
Architectural differentiation
 Score I0
 Score II7
 Score III38
Nuclear pleomorphism
 Score I0
 Score II4
 Score III41
Number of mitoses
 Score I3
 Score II9
 Score III33
Ki-67 tumor expression (%)
 Mean ± SD67 ± 18
EGFR expression
AR status
 Positive (>10%)8
CK5/6 expression
Chemotherapy regimen
 6 courses of FEC1009
 3 courses of FEC100 followed by 3 courses of docetaxel41
 Breast-conserving surgery37
pCR (ypT0/is ypN0)b
  • aClinical stage according to the seventh edition of the American Joint Committee on Cancer (AJCC) staging manual (tumor size assessed with ultrasound scan, lymph node involvement, and metastasis assessed both with ultrasound scan and with FDG-PET, metastasis status assessed with FDG-PET).

  • bpCR is defined as ypT0/is ypN0: no invasive residual in the breast and nodes; in situ breast residuals allowed.