Table 4.

Comparison of refined and unrefined metagenes in the CHEMO data set

HR (95% CI)Pc Index
Proliferation metagene (ER+HER2, n = 350)
 Refined1.51 (1.07–2.14)0.02060.63
 Unrefined1.62 (0.95–2.76)0.07750.59
ER-related metagene (ER+HER2, n = 350)
 Refined0.46 (0.31–0.70)0.00030.67
 Unrefined0.54 (0.33–0.91)0.01920.61
CTM (ERHER2 or HER2+, n = 205)
 Refined0.57 (0.41–0.77)0.00040.65
 Unrefined0.57 (0.39–0.83)0.00360.63

Abbreviation: CTM, consensus T cell–related metagene.