Table 1.

Baseline patient characteristics

CharacteristicParts A–C
(n = 80)
Part D
(n = 9)
All parts
(n = 89)
Gender, n (%)
 Male37 (46.3)37 (41.6)
 Female43 (53.8)9 (100.0)52 (58.4)
Age, years
 Mean616161
 Range36–8255–6935–82
Ethnic origin, n (%)
 African American3 (3.8)3 (3.4)
 Caucasian74 (92.5)8 (88.9)82 (92.1)
 Hispanic3 (3.8)1 (11.1)4 (4.5)
ECOG PS, n (%)
 034 (42.5)6 (66.7)40 (44.9)
 143 (53.8)2 (22.2)45 (50.6)
 23 (3.8)1 (11.1)4 (4.5)
Tumor type, n (%)a
 Colorectal25 (31.3)25 (28.1)
 Breast10 (12.5)9 (100.0)19 (21.3)
 Sarcoma11 (13.8)11 (12.4)
 NSCLC6 (7.5)6 (6.7)
 Renal5 (6.3)5 (5.6)
 Pancreas5 (6.3)5 (5.6)
 Melanoma3 (3.8)3 (3.4)
 Ovary2 (2.5)2 (2.2)
 Other13 (16.3)13 (14.6)

Abbreviation: PS, performance status.

  • aA detailed summary of baseline pathologic diagnosis, per Parts A–D of the study, is included in Supplementary Table S1.