Table 2.

89Zr pharmacokinetics in whole blood samples

Mean (±SD)Mean (±SD)
ParameterCohort 1 (n = 2)Cohort 2 (n = 6)
Cl (L/h)0.066 (0.014)0.033 (0.004)
Vd (L)6.66 (1.433)4.90 (0.876)
t1/2 (h)70.36 (0.297)105.17 (22.131)

NOTE: Cohort 1, ∼1 mg 89Zr-labeled MMOT0530A; Cohort 2, ∼1 mg 89Zr-labeled MMOT0530A supplemented with unlabeled MMOT0530A to a total of 10 mg MMOT0530A.