89Zr pharmacokinetics in whole blood samples
| Mean (±SD) | Mean (±SD) | |
|---|---|---|
| Parameter | Cohort 1 (n = 2) | Cohort 2 (n = 6) |
| Cl (L/h) | 0.066 (0.014) | 0.033 (0.004) |
| Vd (L) | 6.66 (1.433) | 4.90 (0.876) |
| t1/2 (h) | 70.36 (0.297) | 105.17 (22.131) |
NOTE: Cohort 1, ∼1 mg 89Zr-labeled MMOT0530A; Cohort 2, ∼1 mg 89Zr-labeled MMOT0530A supplemented with unlabeled MMOT0530A to a total of 10 mg MMOT0530A.