Table 2.

Mean MV score in relation to clinicopathologic parameters in four independent datasets

Uppsala (N = 253)Stockholm (N = 159)NKI (N = 295)Rotterdam (N = 286)
VariableMean MV score±SDPMean MV score±SDPMean MV score±SDPMean MV score±SDP
ER
 Positive48.116.835.815.958.613.451.817.6
 Negative43.318.00.12833.613.70.48262.514.50.04055.615.10.094
PR
 Positive47.917.235.115.1
 Negative43.514.50.23836.116.70.722
Elston–Ellis grade
 Ia53.215.737.012.760.614.258.414.6
 II47.817.60.07139.917.80.68260.212.30.98358.716.60.999
 III39.713.8<0.00130.912.80.17958.214.60.47151.616.30.527
Nodal status
 Negative49.816.935.715.759.314.3
 Positive43.516.20.00535.515.80.95259.813.20.752
Tumor size
 ≤20 mm51.717.037.015.059.714.1
 >20 mm43.115.8<0.00133.615.90.17559.413.30.830
Age
 ≤5041.313.532.814.659.613.551.918.6
 >5049.217.40.00236.715.80.13958.815.60.75853.515.60.439
Chemotherapy
 Yes42.212.431.716.560.212.5
 No48.317.00.08736.315.20.14659.114.40.495
Endocrine therapy
 Yes46.017.436.216.759.913.5
 No48.616.30.25233.511.90.33159.513.80.839
PAM50
 Luminal Aa52.514.536.912.060.311.255.716.1
 Luminal B39.714.2<0.00126.811.20.00853.513.90.01645.116.6<0.001
 HER2-enriched42.313.10.00432.09.50.66262.212.10.91852.312.90.808
 Basal-like42.018.70.00735.420.40.99262.215.80.98752.617.20.776
 Normal-like57.917.50.34549.615.10.00361.415.90.95765.916.70.047
  • NOTE: P value calculated using Student t test unless otherwise stated.

  • aReference group, P value based on ANOVA with post hoc Tukey analysis. In bold: significant P value of < 0.05.