Table 2.

Multivariate analysis of SMARCA4 expression in the Director's Challenge Study

Multivariate analysisMultivariate analysis (no adjuvant treatment)
VariableHR (95% CI)PHR (95% CI)P
SMARCA4 (212520_s_at)
 Low expression1.01.0
 Intermediate expression0.7 (0.5–0.9)0.010.7 (0.4–1.1)0.09
 High expression0.6 (0.4–0.8)0.0020.4 (0.2–0.8)0.01
Age
 <65 years1.01.0
 ≥65 years1.6 (1.2–2.1)<0.0011.8 (1.1–2.9)0.01
Stage
 I1.01.0
 II–III3.1 (2.4–4.1)<0.0013.8 (2.5–5.9)<0.001
Gender
 Female1.01.0
 Male1.3 (1.0–1.7)0.051.2 (0.8–1.9)0.40
Differentiation
 Well1.01.0
 Moderate0.9 (0.6–1.3)0.510.9 (0.5–1.6)0.60
 Poorly1.1 (0.7–1.6)0.841.0 (0.5–1.9)0.90