Table 1.

The 6-gene hypoxia classifier

Illumina Probe IDEntrez gene IDSymbolaGene nameEmbedded ImageEmbedded ImageEmbedded Image
ILMN_16769841649DDIT3DNA damage–inducible transcript 38.698.050.18
ILMN_174496330001ERO1AEndoplasmic reticulum oxidoreductase α10.289.430.57
ILMN_1777513147040KCTD11Potassium channel tetramerization domain containing 116.886.500.22
ILMN_23816978974P4HA2Prolyl 4-hydroxylase, α polypeptide II9.208.690.35
ILMN_16918848614STC2Stanniocalcin 28.107.050.70
ILMN_165563711045UPK1AUroplakin 1A6.175.540.29
  • NOTE: The classifier parameters Embedded Image, Embedded Image, and Embedded Image were derived from the training cohort with 11 more hypoxic (low ABrix) and 31 less hypoxic (high ABrix) tumors based on Illumina WG-6 expression array data.

  • aHUGO gene symbols are provided. Previous gene symbol for ERO1A was ERO1L.