Table 1.

Patient characteristics at baseline

CharacteristicFull analysis set (N = 132)
Median age, years (range)60 (22–84)
Sex
 Male, n (%)66 (50)
ECOG performance status, n (%)a
 047 (36)
 184 (64)
Primary cancer, n (%)
 Liposarcoma39 (30)
 Breast20 (15)
 Colon19 (14)
 HNSCC10 (8)
 Mantle cell lymphoma7 (5)
 Sarcoma5 (4)
 NSCLC (adenocarcinoma)4 (3)
 Melanoma3 (2)
 Ovarian3 (2)
 NSCLC (SCC)2 (2)
 Other20 (15)
Number of prior systemic antineoplastic therapies, n (%)b
 0/133 (25)
 2/355 (42)
 4+42 (32)
Number of patients who received prior surgery, n (%)a125 (95)
Number of patients who received prior radiotherapy, n (%)c68 (52)
  • Data cutoff: April 24, 2014.

  • Abbreviations: ECOG, Eastern Cooperative Oncology Group; HNSCC, head and neck squamous cell carcinoma; NSCLC, non-small cell lung cancer; SCC, squamous cell carcinoma.

  • aUnknown in 1 patient.

  • bUnknown in 2 patients.

  • cUnknown in 4 patients.