Table 2.

Association between PD-L1, IDO-1, B7-H4, TILs and clinicopathologic variables in cohort No. 2

ParameterStratificationPD-L1 lowPD-L1 highPIDO-1 lowIDO-1 highPB7-H4 lowB7-H4 highP
SexMale168570.0051461390.289190590.261
Female3121622326
Age<70 y157500.3771311320.791186500.271
>70 y40930283514
StageI–II112420.031921000.293135370.527
III–IV851669598227
HistologyAdenocarcinoma83190.06862640.32310212<0.0001
Squamous cell carcinoma992987769546
Other16111320256
CD3Low115180.000398660.0004109390.125
High90426910112028
CD8Low12116<0.000110263<0.0001108390.111
High84446510412128
CD20Low114230.01210962<0.0001115370.6842
High91376111111834