Table 2.

Performance of FIT or Fn alone and in combination with other bacteria for colorectal cancer diagnosis

Variablesa,bFITFnFn + FIT4-Bac4-Bac + FIT
Sensitivity70.3%82.0%92.8%83.8%92.8%
Specificity98.3%80.7%79.8%83.2%81.5%
PPV97.5%79.8%81.1%82.3%82.4%
NPV78.0%82.8%92.2%84.6%92.4%
  • Abbreviations: NPV, negative predictive value; PPV, positive predictive value.

  • a230 Subjects (111 colorectal cancer and 119 healthy controls) with FIT results in Hong Kong cohort were included.

  • b4-Bac includes Fn, Bc, Ch, and m7.