Table 5.

Tissue androgen

P
Degarelix (A)Degarelix + bicalutamide (B)LHRH agonist + bicalutamide (C)OverallaA vs. BbA vs. CbB vs. Cb
Mean DHT, ng/g (SD)0.87 (0.61)0.26 (0.07)0.23 (0.10)<0.001<0.001<0.0010.403
Mean testosterone, ng/g (SD)0.03 (0.02)0.02 (0.01)0.02 (0.01)0.409
Mean DHEA, ng/g (SD)23.24 (10.02)20.68 (11.81)18.48 (12.80)0.617
Mean androstenedione, ng/g (SD)0.21 (0.14)0.23 (0.19)0.18 (0.13)0.805
Mean 4-pregnen-17-ol-3,20-dione, ng/g (SD)0.06 (0.03)0.08 (0.04)0.07 (0.07)0.360
Androsterone, ng/g (SD)1.34 (0.77)1.12 (1.30)1.10 (1.03)0.241
Pregnenolone, ng/g (SD)11.28 (4.94)10.96 (4.84)8.80 (6.59)0.238
Progesterone, ng/g (SD)0.08 (0.06)0.07 (0.03)0.07 (0.05)0.426
5-pregnan-3,20-dione, ng/g (SD)0.11 (0.04)0.18 (0.14)0.12 (0.14)0.388
17-OHpregnenolone, ng/g (SD)4.16 (2.00)4.23 (2.49)3.16 (2.67)0.451
Pregnan-3-ol-20-one, ng/g (SD)0.06 (0.03)0.08 (0.06)0.05 (0.03)0.276
5a-androstan-3,17-dione, ng/g (SD)0.53 (0.28)0.51 (0.37)0.41 (0.42)0.340
  • Abbreviation: T, testosterone.

  • aKruskall–Wallis H test.

  • bMann–Whitney test.