Table 1.

Performance of Fn alone and in combination with other bacteria for colorectal cancer diagnosis

VariableFnCombination of Fn, Bc, Ch, and m7
AUROC0.8680.886
Cut-offa0.00070720.001774
Sensitivity77.7%77.7%
Specificity79.5%81.5%
PPV76.3%78.1%
NPV80.7%81.1%
  • Abbreviations: AUROC, area under receiver operating characteristics curve; NPV, negative predictive value; PPV, positive predictive value.

  • aThe best cut-off values that maximize sensitivity and specificity were used. n = 370 (170 colorectal cancer and 200 healthy controls).