Table 1.

Baseline characteristics of the 210 subjects

Patient characteristicsCancer (N = 150)Control (N = 60)P
Age at surgery (IQR), y68 (62–75)63 (55–73)0.007
Gender
 Male (%)63 (42%)33 (55%)0.094
 Female (%)87 (58%)27 (45%)
Race
 White (%)120 (80%)51 (85%)0.087
 Black (%)19 (13%)3 (5%)
 Other (%)11 (7%)6 (10%)
Stage
 IA–IB (%)136 (91%)NANA
 IIA (%)14 (9%)NA
Histology
 Adenocarcinoma (%)121 (81%)NANA
 Squamous cell (%)26 (17%)NA
 Adenosquamous (%)3 (2%)NA
Smoking status
 Current (%)27 (18%)7 (12%)0.176
 Former (%)87 (58%)34 (57%)
 Never (%)31 (21%)19 (32%)
Pack-year (IQR)30 (10–50)20 (0–35)0.010
COPD (%)41 (27%)12 (20%)0.370
FEV1 % predicted (IQR)84 (70–99)85 (70–100)0.861
FVC % predicted (IQR)92 (80–103)87 (80–110)0.682
FEV1/FVC % ratio (IQR)73 (68–78)77 (70–79)0.080
Nodule size, cm2 (1.5–3)1.5 (1.1–3)0.01
 <16 (4%)13 (22%)0.001
 1–252 (35%)19 (32%)
 >292 (61%)28 (47%)
Nodule volume, cm34.19 (1.77–14–14)1.6 (0.52–18.12)0.001
  • NOTE: Nodule size % <1, 1–2, >2 cm.

  • Abbreviations: FEV1, forced expiratory volume in 1 second; IQR, interquartile range.