Table 2.

CD4 and CD8 immune outcomes in the peripheral blood and in the SLNs by route of vaccine administration

Route of vaccine administration
IL, n = 19IN, n = 19ILN, n = 16
n (%)Exact 95% CIn (%)Exact 95% CIn (%)Exact 95% CIP
Overall CD4 PB
 Immune respondersa16 (84.2)60.4–96.617 (89.5)66.9–98.710 (66.7)38.4–88.20.30
Overall CD8 PB
 Immune respondersb6 (85.7)42.1–99.63 (42.9)9.9–81.67 (87.5)47.3–99.70.17
Overall CD4 SLN
 Immune respondersc10 (71.4)41.9–91.611 (91.7)61.5–99.811 (78.6)49.2–95.30.54
  • Abbreviation: PB, peripheral blood.

  • aOne patient (ILN) not evaluable for overall CD4 peripheral blood immune response.

  • b22 total HLA-A2+ patients evaluated for CD8 peripheral blood immune response (7 IL, 7 IN, 8 ILN).

  • c40 total patients evaluated for SLN CD4 immune response (14 IL, 12 IN, 14 ILN).