Table 1.

Univariate and multivariate analyses of the imaging subtype and clinical risk factors for predicting RFS in the discovery cohort

UnivariateMultivariate
PredictorsHR (95% CI)PHR (95% CI)P
Imaging subtypea2.11 (1.19–3.71)0.010b2.79 (1.21–6.44)0.016b
Age0.79 (0.53–1.19)0.2600.57 (0.30–1.09)0.087
ER0.60 (0.23–1.55)0.2890.57 (0.11–2.95)0.499
PR0.67 (0.25–1.75)0.4090.30 (0.06–1.50)0.143
HER20.75 (0.24–2.29)0.6100.49 (0.10–2.34)0.370
Histologic typec0.97 (0.42–2.24)0.9400.73 (0.23–2.34)0.602
Lymph node status3.43 (1.16–10.14)0.026b3.42 (0.64–18.20)0.149
Molecular subtyped1.49 (0.84–2.65)0.177
  • aImage subtype was treated as a continuous variable, that is, subtype 1 was coded as 1, subtype 2 was coded as 2, subtype 3 was coded as 3.

  • bP < 0.05.

  • cThe invasive ductal carcinoma was coded as 1 and other types as 0.

  • dMolecular subtype includes luminal, HER2+, and triple-negative, and it was not adjusted in multivariate analysis.