Table 4.

Response data

0.6 mg/kg (n = 6)0.9 mg/kg (n = 9)1.2 mg/kg (n = 13)aOverall (n = 28)
n (%)n (%)n (%)n (%)
Partial response/ORRb2 (33.3)3 (33.3)2 (15.4)7 (25.0)
95% CI4.3–77.77.5–70.11.9–45.410.7–44.9
Stable disease2 (33.3)6 (66.7)9 (69.2)17 (60.7)
95% CI4.3–77.729.9–92.538.6–90.940.6–78.5
Progressive disease2 (33.3)02 (15.4)4 (14.3)
95% CI4.3–77.70–33.61.9–45.44.0–32.7
Disease control ratec ≥ 6 months3 (50.0)5 (55.6)6 (46.2)14 (50.0)
95% CI11.8–88.221.2–86.319.2–74.930.6–69.4
  • aOne patient not evaluable for response based upon ineligibility.

  • bORR is defined as the proportion of patients who achieved either confirmed complete or partial response, as no patients achieved complete response, ORR = partial response in this study.

  • cDisease control rate is defined as the proportion of patients evaluable for response who meet the criteria for complete response, partial response, or stable disease.