Table 3.

Classification performance of wavelength subregions of HSI for the detection of head and neck cancer with intrapatient classification and interpatient classification

Primary siteClassification methodWavelength range (nm)AUCAccuracySensitivitySpecificity
Oral cavityIntrapatient classification450–6000.87 ± 0.1182% ± 11%81% ± 13%82% ± 10%
605–8500.89 ± 0.1284% ± 12%83% ± 12%85% ± 12%
855–9000.76 ± 0.1472% ± 11%73% ± 11%71% ± 12%
450–9000.95 ± 0.0589% ± 8%90% ± 7%90% ± 8%
Interpatient classification450–6000.88 ± 0.1282% ± 11%82% ± 11%81% ± 12%
605–8500.82 ± 0.1177% ± 11%78% ± 10%76% ± 12%
855–9000.71 ± 0.1167% ± 9%67% ± 9%66% ± 11%
450–9000.91 ± 0.1085% ± 10%85% ± 9%84% ± 12%
ThyroidIntrapatient classification450–6000.97 ± 0.0693% ± 8%93% ± 9%95% ± 6%
605–8500.95 ± 0.0691% ± 9%90% ± 10%92% ± 7%
855–9000.93 ± 0.0989% ± 10%88% ± 12%90% ± 8%
450–9000.96 ± 0.0592% ± 7%92% ± 9%94% ± 6%
Interpatient classification450–6000.92 ± 0.0787% ± 9%86% ± 9%88% ± 9%
605–8500.94 ± 0.0588% ± 6%88% ± 6%88% ± 6%
855–9000.84 ± 0.1178% ± 11%77% ± 10%79% ± 10%
450–9000.91 ± 0.0986% ± 10%85% ± 11%87% ± 9%