Table 1.

Characteristics of the study populations, including histology and molecular subtype of the LGGs, patient age at diagnosis, and gender. Count and percentage are provided for categorical variables

TCGA cases (test set) (n = 125)NYU cases (validation set) (n = 82)
Histology
 Astrocytoma
  Grade II8 (6%)12 (15%)
  Grade III30 (24%)28 (34%)
 Oligodendroglioma
  Grade II33 (26%)22 (27%)
  Grade III21 (17%)16 (20%)
 Oligoastrocytoma
  Grade II17 (14%)1 (1%)
  Grade III16 (13%)3 (4%)
Molecular subtype
IDHmut-Codel34 (27%)31 (52%)a
IDHmut-Noncodel68 (54%)22 (37%)a
IDHwt23 (18%)7 (12%)a
Age at diagnosis (years)
 Median45.545
 Range20–7521–82
Gender
 Female63 (50%)38 (46%)
 Male62 (50%)44 (54%)
  • aMolecular subtype was available for a total of 60 cases among the NYU cohort.