Table 1.

Clinical characteristics of patients

CharacteristicsCohort (n = 93)
Age at diagnosisYears
 Median60
 25th–75th percentiles52–67
 Range34–86
Gendern
 Female54
 Male39
Smoking historyn
 Nonsmoker70
 Smoker10
 NDa13
Histology type at initial diagnosisn
 Adenocarcinoma86
 Squamous2
 Small cell3
 NDa2
Clinical stage at initial diagnosisn
 II–III6
 IV77
 NDa10
Treatment history before osimertinibn
 Gefitinib42
 Erlotinib15
 Icotinib22
 Afatinib1
 Gefitinib + afatinib3
 Gefitinib + erlotinib2
 Gefitinib + bevacizumab1
 Erlotinib + afatinib1
 Icotinib + erlotinib1
 Icotinib + afatinib1
 TKI (NDa)1
 Bevacizumab2
 Treatment-naive1
Post-osimertinib specimensn
Tumor tissue
 FFPE5
 Fresh tumor5
cfDNA
 Plasma81
 Pleural effusion2
  • aNot determined.