Table 2.

(a) Genes significantly altered in IHC relative to EHC; (b) Genes significantly altered in EHC relative to IHC

GeneIHC mutated (n = 158)EHC mutated (n = 37)ORP valueq value
(a)
 IDH14627.1370.0010.011
 BAP1300Inf0.0020.013
 FGFR2200Inf0.0160.087
(b)
 KRAS11140.1250.0000.000
 SMAD48110.1280.0000.001
 TP5328180.2300.0000.007
 STK11140.0540.0050.031
  • Abbreviations: EHC, extrahepatic cholangiocarcinoma; IHC, intrahepatic cholangiocarcinoma; Inf, infinite.