Table 1.

Acute GvHD pre- and post-aDLI

PatientaDLI dose level and dayPre-aDLIPost-aDLI
Acute GvHD time, grade (stage)
001Level 1, D+35NoneNone
002Level 1, D+35NoneNone
003Level 1, D+35NoneNone
004Level 1, D+42NoneNone
005Level 2, D+42D+22 grade 2 (S2,GI 1, L0)D+98 grade 2 (S3,GI 0, L1)
010Level 2, D+34NoneNone
012Level 2, D+35NoneNone
013None givenaNoneN/E
025None givenbNoneN/E
026Level 2, D+35NoneD+52 grade 4 (S0,GI 4, L4)
027Level 2, D+42NoneNone
028cNone givenN/EN/E
030Level 2, D+42NoneNone
033Level 2, D+35NoneD+54 grade 1 (S2,GI 0, L0)
035Level 2, D+35NoneNone
015Level 3, D+36NoneD+63 grade 3 (S3,GI 3, L0)
016Level 3, D+35NoneD+62 grade 3 (S2,GI 3, L0)
018Level 3, D+35NoneNone
023Level 3, D+35NoneD+89 grade 3 (S0,GI 1, L3)
  • NOTE: Level 1, 103 CD3 T cells/kg; level 2 104 CD3 T cells/kg; level 3, 105 CD3 T cells/kg.

  • Abbreviations: GI, gastrointestinal; L, liver; S, skin.

  • aDied D+32 of bacterial sepsis prior to infusion of aDLI.

  • bDonor not able to donate.

  • cNonengraftment followed by autologous reconstitution.