Table 2.

GL-ONC1–related adverse events

Drug-related events, number of occurrences (number of patients)Grade 1Grade 2Grade 3Grade 4
Gastrointestinal disorders
 Diarrhea2 (2)
 Nausea4 (2)1 (1)
 Vomiting4 (4)
 Flatulence3 (1)
 Abdominal pain6 (4)1 (1)2 (2)
 Ascites6 (2)
Generalized symptoms
 Fatigue1 (1)2 (1)
 Pyrexia16 (8)3 (3)
 Chills2 (1)
Abnormal blood parameters
 Alanine aminotransferase increased1 (1)
 Aspartate aminotransferase increased1 (1)
 Alkaline phosphatase increased1 (1)
 Creatinine increased2 (2)
 Gamma-glutamyltransferase increased1 (1)
 Lymphocyte count decreased19 (7)7 (5)-
 C-reactive protein increased20 (7)
 Hyperhidrosis1 (1)
 Cough1 (1)
 Pain in extremity1 (1)
 Herpes simplex virus infection2 (2)