Table 4.

Multivariate logistic and Cox regression analyses of BRCA1/2 genes

Logistic regressionCox regression
VariableAOR (95% CI)PAdjusted HRP
BRCA1/2 Mutations
 Absent1 (reference)1 (reference)
 Present1.77 (1.26–2.46)0.0030.32 (0.11–0.94)0.04
Gender
 Female1 (reference)1 (reference)
 Male1.36 (0.95–1.97)0.110.42 (0.15–1.20)0.10
Age at diagnosis0.99 (0.97–1.00)0.201.04 (0.99–1.10)0.12
Primary tumor site
 Head1 (reference)1 (reference)
 Body/Tail1.39 (0.89–2.17)0.160.21 (0.04–1.03)0.05
Family history of cancer, N (%)
 No1 (reference)1 (reference)
 Yes1.07 (0.79–1.44)0.661.10 (0.44–2.75)0.84
Pathological T Stage
 T1/T21 (reference)1 (reference)
 T30.98 (0.61–1.59)0.950.85 (0.18–4.09)0.84
Pathological N Stage
 N01 (reference)1 (reference)
 N10.86 (0.58–1.29)0.473.48 (1.06–11.39)0.04
Margin Involvement at surgery
 No1 (reference)1 (reference)
 Yes0.90 (0.63–1.29)0.581.66 (0.58–4.75)0.34
CA 19–9, U/mL
 Normal1 (reference)1 (reference)
 Elevated0.96 (0.68–1.35)0.822.15 (0.71–6.48)0.17
Adjuvant chemotherapy
 No1 (reference)1 (reference)
 Yes1.04 (0.69–1.57)0.850.63 (0.17–2.31)0.49
  • Abbreviations: AOR, adjusted odds ratio; CA, carbohydrate antigen; HR, hazard ratio; N, node; T, tumor.