Table 1.

Association of CD3+ T-cell densities at the invasive tumor margin with clinicopathologic characteristics in stage III colon cancers with deficient and proficient DNA mismatch repair

Deficient mismatch repair tumorsProficient mismatch repair tumors
NMedian (IQR)PNMedian (IQR)P
Age≤59 y12436.1 (19.4–58.5)0.085116125.7 (15.1–42.3)0.8938
>59 y15440.0 (24.2–73.8)12225.6 (15.8–45.5)
GenderFemale15739.0 (22.9–64.0)0.5497W11926.8 (15.8–41.8)0.9595W
Male12135.6 (21.5–66.0)16424.8 (15.1–45.0)
RaceAsian720.0 (13.3–35.6)0.0668KW1519.3 (11.8–30.5)0.1125KW
Black1430.2 (15.0–51.9)934.0 (20.0–46.3)
White25238.3 (23.1–67.4)25226.3 (15.3–44.8)
SmokingEver7249.6 (24.0–79.4)0.0097W8826.9 (15.4–41.8)0.8930W
Never12431.7 (21.7–53.2)10924.6 (14.6–42.7)
T stageT1 or T22457.3 (33.2–82.7)0.0188KW3543.3 (30.0–71.7)0.0002KW
T321537.2 (20.9–66.4)20624.0 (15.1–41.6)
T43930.2 (20.6–52.4)4222.3 (13.0–41.7)
N stageN116641.0 (24.2–70.5)0.0300W16128.2 (17.4–46.3)0.0578W
N211231.3 (19.2–60.3)12223.0 (14.0–38.9)
T and N StageT1-3N114344.5 (24.9–73.9)0.0059W14029.7 (18.4–47.3)0.0138W
T4 or N213531.0 (19.2–55.8)14322.8 (14.0–39.7)
Tumor LocationRight24438.7 (23.1–67.1)0.0369W12731.4 (17.4–48.0)0.0315W
Left2727.5 (16.5–48.9)15623.3 (14.5–38.8)
GradeHigh14544.9 (26.3–74.5)0.0013W6726.5 (14.4–46.9)0.9272W
Low13331.2 (19.1–55.6)21625.5 (15.2–42.9)
BRAF/KRAS mutation statusBoth wild-type10338.2 (21.5–57.5)0.9419KW16524.1 (14.9–42.7)0.4675KW
KRAS mutated3637.0 (23.5–66.8)8630.4 (17.4–46.6)
BRAF mutated12935.7 (21.0–70.5)2019.5 (14.9–40.3)
  • Abbreviations: W, Wilcoxon rank-sum tests; KW, Kruskal Wallis test.