Table 2.

Clinical performance characteristics of training and validation cohort samples for models consisting of biomarkers only and biomarkers with clinical characteristics (Videssa Breast)

TrainingValidation
Biomarkers onlyBiomarkers w/ClinicalVidessa BreastVidessa Breast (age ≥ 50)Videssa Breast (age ≥ 50, BI-RADS 3 & 4 Only)
TN193179645454
FP191205928685
TP6780363526
FN185222
Sens79% (68%–87%)94% (86%–98%)95% (81%–99%)95% (80%–99%)93% (75%–99%)
Spec50% (45%–55%)47% (42%–52%)41% (33%–49%)39% (31%–47%)39% (31%–48%)
PPV26% (21%–32%)28% (23%–34%)28% (21%–37%)29% (21%–38%)23% (16%–33%)
NPV92% (87%–95%)97% (93%–99%)97% (89%–99%)96% (87%–99%)96% (87%–99%)