Table 2.

TEAEs suspected to be avadomide-related

AEs, n (%)Any grade (n = 34)Grade 3/4 AE (n = 34)
≥1 TEAE29 (85)14 (41)
Fatigue15 (44)1 (3)
Neutropenia10 (29)9 (27)
Diarrhea5 (15)
Alopecia4 (12)
Pruritus4 (12)
Maculopapular rash4 (12)
Abdominal distension3 (9)
Nausea3 (9)
Vomiting3 (9)
Asthenia3 (9)
Decreased appetite3 (9)
Hot flush3 (9)
Anemia2 (6)
Dry mouth2 (6)
Pneumonia2 (6)2 (6)
Muscle spasms2 (6)
Dysgeusia2 (6)
Headache2 (6)
Peripheral neuropathy2 (6)
Thrombocytopenia1 (3)1 (3)
Cataract1 (3)1 (3)
Pyrexia1 (3)1 (3)
Pneumocystis jirovecii pneumonia1 (3)1 (3)
Muscular weakness1 (3)1 (3)
Angioedema1 (3)1 (3)
  • NOTE: Values shown are n (%). Avadomide-related TEAEs of any grade occurring in >1 patient and all grade 3/4 TEAEs are included.