Table 2.

Adverse events (grades 3 and 4)

Adverse eventNo. of patients (#)
Lymphopenia29
Neutropenia29
Thrombocytopenia29
Anemia25
Infectiona17
Febrile neutropenia12
Metabolic disorders12
Hypoxia8
Nausea/vomiting6
Dyspnea4
Diarrhea3
Fatigue3
Hypotension3
Cystitis2
Hemorrhageb2
Oliguria2
Renal failurec2
Syncope2
Ureteral obstructiond2
Dysphagia1
Confusion1
  • aIncludes positive surveillance blood cultures.

  • bAssociated with radiation colitis in 1 patient and with an in situ cervical carcinoma in 1 patient.

  • cAssociated with progressing pelvic tumor in 1 patient.

  • dAssociated with progressing pelvic tumors in 2 patients.