Table 7.

Leukemic growth delay summary and clinical scoring for the 2 treatment schedules for xenografts ALL-8 and ALL-19

Median EFS (days)
Treatment scheduleaControlTreatedEFS T-C (days)EFS T/CP valuebMedian response score
ALL-8Schedule A8.919.810.92.20.002PD2
Schedule B8.931.923.03.60.002SD
ALL-19Schedule A6.613.67.02.00.584PD2
Schedule B6.631.224.64.70.002CR
  • aSchedule A, twice daily × 7 days; schedule B, twice daily × 5 days × 3 weeks.

  • bStatistically significant results.