Table 2.

Sites of metastasis at diagnosis

Sites of mets at diagnosisBRAF wt TOT = 540 N (%)BRAF mut class 1 TOT = 92 N (%)BRAF mut class 2 TOT = 12 N (%)BRAF mut class 3 TOT = 13 N (%)PPaPbPc
LiverYes387 (72)44 (48)8 (67)10 (77)<0.00010.67280.35790.0740
No153 (28)48 (52)4 (33)3 (23)
LungYes104 (19)15 (16)2 (18)2 (15)0.61011.00001.00001.0000
No436 (81)77 (84)10 (82)11 (85)
Distant nodesYes109 (20)38 (41)2 (18)2 (15)<0.00011.00000.12340.1245
No431 (80)54 (59)10 (82)11 (85)
PeritoneumYes102 (19)29 (31)3 (27)0 (0)0.00980.09570.75100.0176
No438 (81)63 (69)9 (73)13 (100)
OtherYes60 (11)12 (13)1 (10)3 (23)0.7290.59301.00000.3928
No480 (89)80 (87)11 (90)10 (77)
  • aClass 2 versus class 3.

  • bClass 1 versus class 2.

  • cClass 1 versus class 3.