Table 2.

Multivariable Cox proportional hazards modeling of AAstroENC model scores adjusting for clinical and pathologic variables.

Dataset V1,AA (n = 31)Dataset V2,AA (n = 93)
ParameterHR (95% CI)PHR (95% CI)P
AAstroENC score4.62 (1.31–16.23)0.0172.58 (1.38–4.83)0.0029
Age at the time of surgery0.27 (0.091–0.82)0.020.74 (0.32–1.69)0.47
Gleason score ≤6Reference1.00Reference1.00
Gleason score = 71.89 (0.86–4.13)0.110.68 (0.19–2.48)0.57
Gleason score ≥81.09 (0.42–2.84)0.851.07 (0.31–3.78)0.91
Preoperative PSA value2.60 (1.11–6.10)0.0271.75 (0.82–3.74)0.14
Presence of SVI3.27 (1.21–8.86)0.0192.53 (1.20–5.33)0.014
Presence of ECE0.82 (0–infinity)1.000.94 (0.23–3.76)0.93
Positive surgical margins0.77 (0.30–1.92))0.571.18 (0.61–2.31)0.62
Pathologic stage pT2xReference1.00Reference1.00
Pathologic stage pT3x0.62 (0–infinity)1.001.36 (0.81–2.28)1
  • Note: Predictors with significant P values in bold.