Table 1.

IMpassion130 demographics, ITT and PD-L1 positive population.

Atezolizumab + paclitaxel protein-bound (ITT)Placebo + paclitaxel protein-bound (ITT)Atezolizumab + paclitaxel protein-bound (PD-L1 positive)Placebo + paclitaxel protein-bound (PD-L1 positive)
Demographic parametersN = 451 (%)N = 451 (%)N = 185 (%)N = 184 (%)
Sex
 Male3110
 Female448450184184
Age
 Mean (SD)54.3 (12.3)55.4 (12.1)53.7 (12.9)53.6 (12)
 Median55565353
 Min, max (years)20–8226–8626–8228–85
Age group
 18–4063 (14)51 (11.3)31 (16.8)24 (13)
 41–64284 (63)285 (63.2)111 (60)117 (63.6)
 ≥65104 (23.1)115 (25.5)43 (23.2)43 (23.4)
Race
 White308 (68.3)301 (66.7)125 (67.6)129 (70.1)
 Asian85 (18.8)76 (16.9)38 (20.5)28 (15.2)
 Black or African American26 (5.8)33 (17.3)9 (4.9)14 (17.6)
 American Indian or Alaska Native17 (3.8)23 (5.1)8 (4.3)9 (4.9)
 Native Hawaiian/Pacific Islander1 (0.2)0 (0)0 (0)0 (0)
Othera14 (3.1)18 (4)5 (2.7)4 (2.2)
ECOG
 0256 (56.9)270 (60)107 (57.8)112 (60.9)
 1193 (42.9)179 (39.8)77 (41.6)72 (39.1)
 21 (0.2)1 (0.2)1 (0.5)0 (0)
  • Abbreviation: ECOG, Eastern Cooperative Oncology Group.

  • aOther, unknown, multiple.