Table 1A.

Levels of HIF-1α (total), HIF-2α, and HAF within patients by clinical characteristics included in table are P values for whether HIF-1α, HIF-2α, or HAF values differ significantly by T stage, M stage, or grade (using ANOVA or Kruskall–Wallis test if ANOVA assumptions were violated).

Within patient HIF-1α (total) valuesWithin patient HIF-2α valuesWithin patient HAF values
Staining intensitySEStaining intensitySEStaining intensitySE
Patient characteristicsMeanPMedianPMeanPMedianPMeanPMedianP
All0.0260.0070.1920.0370.0950.023
T Stage0.0050.01<0.001<0.001<0.0010.25
 T10.0280.0070.4190.0650.1640.029
 T20.040.0130.1950.0340.1120.026
 T30.020.0060.0990.0250.0550.019
 T40.0550.0190.1660.0520.0120.004
M Stage0.020.020.010.370.0010.18
 No0.0240.0060.2190.0370.1130.027
 Yes0.0330.0090.1370.0320.0490.017
Tumor grade0.040.010.010.64<0.0010.14
 10.020.0050.4730.0680.210.024
 20.0220.0050.2450.0380.1670.031
 30.0250.0070.1880.0370.1040.024
 40.0350.0110.1210.0310.0380.015