Table 2.

Top 18 genes that correlated with time to recurrence.

Log2 FC post/pre for each patient
Gene symbolGene descriptionGTFB 1002GTFB 1064GTFB 1066GTFB 1046GTFB 722GTFB 974Correlation to recurrence (r, Pearson P < 0.05)
FGF9Fibroblast growth factor 9−1.36−0.66−0.38−0.370.870.77−0.990
CXCL5C-X-C motif chemokine 5−1.410.08−0.341.541.582.60−0.921
IER3Immediate early response 30.20−0.120.520.551.301.91−0.885
AXIN1Axin-1−0.29−0.230.00−0.070.290.04−0.869
SPRY4Sprouty homolog 4−1.11−1.20−0.62−1.160.770.58−0.869
THBS1Thrombospondin-10.07−0.181.141.371.322.37−0.853
CASP3Caspase-3−0.67−0.17−0.50−0.370.241.20−0.839
ITGAVIntegrin alpha-V−0.10−0.01−0.05−0.321.111.14−0.823
CEBPBCCAAT/enhancer-binding protein beta−0.010.290.161.001.280.81−0.816
OASL2′-5′-Oligoadenylate synthetase like0.83−0.88−1.72−2.20−1.79−2.040.817
IFITM1Interferon induced transmembrane protein 11.231.831.33−0.83−1.00−1.400.820
CST2Cystatin SA2.32−0.26−0.69−0.43−0.65−1.210.832
HNF1AHepatocyte nuclear factor 1-alpha1.640.360.010.23−0.10−0.040.839
IRF7Interferon regulatory factor 70.35−0.14−0.52−0.59−0.86−0.510.855
VTCN1V-Set domain containing T cell activation inhibitor 10.07−2.44−4.05−1.47−4.21−5.440.867
MX1MX dynamin-like GTPase 11.070.40−1.09−2.00−1.46−2.460.873
CCNOCyclin O0.48−0.19−1.56−2.80−2.73−3.000.903
HERC6HECT and RLD domain containing E3 ubiquitin ligase 61.000.680.19−1.23−1.68−1.580.919
Time to recurrence (days)5053472792456025
  • Note: Log2 fold change (FC, n = 12) correlated with time to disease recurrence (last row), bold numbers. NanoString transcriptomic data were used. Pearson correlation analysis (|r| > 0.8; P < 0.05).