Table 1.

Patients characteristics.

OverallControlMonoallelicBiallelicP
n180144828
Age at diagnosis [median (IQR)]61.0 (56.0–64.2)61.0 (55.8–64.0)59.0 (55.0–63.5)62.5 (60.0–65.0)0.401a
T group (%)0.281b
T12 (1.1)1 (0.7)1 (12.5)0 (0.0)
T220 (11.1)18 (12.5)0 (0.0)2 (7.1)
T376 (42.2)57 (39.6)4 (50.0)15 (53.6)
T434 (18.9)26 (18.1)2 (25.0)6 (21.4)
TX48 (26.7)42 (29.2)1 (12.5)5 (17.9)
T3/4 = yes (%)110 (83.3)83 (81.4)6 (85.7)21 (91.3)0.623b
N (%)0.197b
N042 (36.8)28 (33.3)5 (83.3)9 (37.5)
N165 (57.0)51 (60.7)1 (16.7)13 (54.2)
N27 (6.1)5 (6.0)0 (0.0)2 (8.3)
N1/2 = yes (%)72 (63.2)56 (66.7)1 (16.7)15 (62.5)0.059b
M = M1 (%)96 (56.5)76 (56.3)2 (28.6)18 (64.3)0.231b
Total Gleason score (G) [median (IQR)]9.0 (7.0–9.0)8.0 (7.0–9.0)9.0 (7.8–9.0)9.0 (9.0–9.0)<0.001a
G ≤ 7 vs. G > 8 = yes (%)117 (72.2)84 (66.1)6 (75.0)27 (100.0)<0.001b
PSA at diagnosis mcg/L [median (IQR)]63.0 (15.4–176.1)53.5 (10.9–162.0)106.0 (34.5–137.0)72.0 (25.5–229.2)0.449a
Prostatectomy Y/N = yes (%)22 (12.2)18 (12.5)2 (25.0)2 (7.1)0.318b
Radiotherapy Y/N = yes (%)67 (37.2)57 (39.6)2 (25.0)8 (28.6)0.450b
  • Abbreviations: IQR, interquartile range T size and extent of the main tumor; M, presence of metastatic disease; N, presence of nodal disease.

  • aKruskal–Wallis test.

  • bFisher exact test.