Table 1.

Number of patients and doses of NUC-1031 and carboplatin by cohort.

CohortNUC-1031 (days 1 and 8, every 3 weeks) × 6 cyclesCarboplatin (day 1 only, every 3 weeks) × 6 cyclesNumber of patients (n = 25)
1750 mg/m2AUC46
2750 mg/m2AUC51
2B500 mg/m2AUC512
3625 mg/m2AUC46