Table 2.

Summary of the most commonly involved regions in CNA

Chromosome regionCytobandLength (Mb)Event%Genes, nGene symbols
chr3: 53, 188, 281–53, 220, 792p21.10.03Loss42.861PRKCD
chr3: 178, 243, 320–178, 531, 406q26.320.29Loss42.861TBL1XR1
chr5: 4, 025, 353–127, 435, 612p15.33–q23.3123.41Gain42.86460
chr6: 32, 560, 987–32, 591, 889p21.320.03Loss57.143HLA-DRA, HLA-DRB1, HLA-DRB5
chr6: 68, 245, 865–87, 035, 064q12–q14.318.79Loss57.1464
chr6: 102, 568, 948–117, 578, 748q16.3–q22.215.01Loss57.1479
chr6: 121, 651, 884–121, 998, 751q22.310.35Loss57.142c6orf170, GJA1
chr6: 151, 726, 681–152, 128, 179q25.10.4Loss57.145ZBTB2, RMND1, c6ofr211, c6orf97, ESR1
chr6: 160, 706, 067–163, 042, 970q25.3–q262.34Loss57.148SLC22A3, LPAL2, LPA, PLG, MAP3K4, MTK1, AGPAT4, PARK2
chr7: 0–37, 224, 176p22.3–p14.237.22Gain42.86230
chr9: 21, 952, 671–21, 976, 825p21.30.02Loss71.431CDKN2A
chr12: 0–5, 440, 239p13.33–p13.315.44Gain57.1447
chr12: 37, 153, 346–132, 349, 534q12–q24.3395.2Gain71.43796
chr16: 0–19, 949, 848p13.3–p12.319.95Gain42.86312
chr16: 79, 529, 380–88, 827, 254q23.2–q24.39.3Gain42.86109
chr18: 3, 006, 092–3, 586, 303p11.310.58Gain42.865MYOM1, MRCL3, MRLC2, TGIF1, DLGAP1
chr19: 52, 173, 665–63, 811, 651q13.32–q13.4311.64Gain42.86618
chr21: 33, 423, 626–46, 862, 008q22.11–q22.313.44Gain42.86159
chrX: 100, 348, 062–100, 668, 066q22.10.32Gain42.868DRP2, TAF7L, TIMM8A, BTK, RPL36A, GLA, HNRNPHA2, ARMCX4
chrX: 152, 713, 724–152, 889, 525q280.18Gain42.869SSR4, PDZD4, L1CAM, LCAP, AVPR2, ARHGAP4, ARD1A, RENBP, HCFC1

NOTE: In all regions smaller than 5 Mb, the genes included are summarized.