Table 2.

Summary of the most commonly involved regions in CNA

Chromosome region	Cytoband	Length (Mb)	Event	%	Genes, n	Gene symbols
chr3: 53, 188, 281–53, 220, 792	p21.1	0.03	Loss	42.86	1	PRKCD
chr3: 178, 243, 320–178, 531, 406	q26.32	0.29	Loss	42.86	1	TBL1XR1
chr5: 4, 025, 353–127, 435, 612	p15.33–q23.3	123.41	Gain	42.86	460
chr6: 32, 560, 987–32, 591, 889	p21.32	0.03	Loss	57.14	3	HLA-DRA, HLA-DRB1, HLA-DRB5
chr6: 68, 245, 865–87, 035, 064	q12–q14.3	18.79	Loss	57.14	64
chr6: 102, 568, 948–117, 578, 748	q16.3–q22.2	15.01	Loss	57.14	79
chr6: 121, 651, 884–121, 998, 751	q22.31	0.35	Loss	57.14	2	c6orf170, GJA1
chr6: 151, 726, 681–152, 128, 179	q25.1	0.4	Loss	57.14	5	ZBTB2, RMND1, c6ofr211, c6orf97, ESR1
chr6: 160, 706, 067–163, 042, 970	q25.3–q26	2.34	Loss	57.14	8	SLC22A3, LPAL2, LPA, PLG, MAP3K4, MTK1, AGPAT4, PARK2
chr7: 0–37, 224, 176	p22.3–p14.2	37.22	Gain	42.86	230
chr9: 21, 952, 671–21, 976, 825	p21.3	0.02	Loss	71.43	1	CDKN2A
chr12: 0–5, 440, 239	p13.33–p13.31	5.44	Gain	57.14	47
chr12: 37, 153, 346–132, 349, 534	q12–q24.33	95.2	Gain	71.43	796
chr16: 0–19, 949, 848	p13.3–p12.3	19.95	Gain	42.86	312
chr16: 79, 529, 380–88, 827, 254	q23.2–q24.3	9.3	Gain	42.86	109
chr18: 3, 006, 092–3, 586, 303	p11.31	0.58	Gain	42.86	5	MYOM1, MRCL3, MRLC2, TGIF1, DLGAP1
chr19: 52, 173, 665–63, 811, 651	q13.32–q13.43	11.64	Gain	42.86	618
chr21: 33, 423, 626–46, 862, 008	q22.11–q22.3	13.44	Gain	42.86	159
chrX: 100, 348, 062–100, 668, 066	q22.1	0.32	Gain	42.86	8	DRP2, TAF7L, TIMM8A, BTK, RPL36A, GLA, HNRNPHA2, ARMCX4
chrX: 152, 713, 724–152, 889, 525	q28	0.18	Gain	42.86	9	SSR4, PDZD4, L1CAM, LCAP, AVPR2, ARHGAP4, ARD1A, RENBP, HCFC1

NOTE: In all regions smaller than 5 Mb, the genes included are summarized.